Functional investigation of the RHD gene promoter: Molecular changes are rarely responsible for variant D phenotype in Thai donors

Key Points

• This research aims to explore the regulation of the RH gene and the factors affecting D antigen expression.
• Analysis of the RHD gene promoter
• Investigation of genomic regions in Thai donors
• Characterization of rare variants
• Examination of gene expression levels.
• Complex regulation of RH gene expression identified
• Rare genomic variants may not significantly impact D antigen expression
• Need for further research into involved genomic regions.