Clinical spectrum, predictive biomarkers, and prognostic implications of peripheral neuropathies in primary Sjögren’s syndrome: a retrospective cohort study

Q: What does this research mean for the field?

Early identification and subtyping of peripheral neuropathies in primary Sjögren’s syndrome (pSS-PN) is crucial for accurate disease assessment and guiding treatment. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Yanqing Wang; Jincheng Pu; Fei Han; Chunrui Li; Yan Chen; Jie Li; Zhenzhen Wu; Shengnan Pan; Jiang Qian; Wei Wang; Jianping Tang; Xuan Wang

doi:10.1186/s40001-026-04192-4

March 9, 2026European journal of medical researchOpen Access

Clinical spectrum, predictive biomarkers, and prognostic implications of peripheral neuropathies in primary Sjögren’s syndrome: a retrospective cohort study

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Key Points

The aim is to identify and subtype peripheral neuropathies associated with primary Sjögren's syndrome for better disease management.
Retrospective cohort study design
Analysis of clinical data from patients with primary Sjögren's syndrome
Identification of predictive biomarkers for neuropathies
Early identification of specific peripheral neuropathies linked to primary Sjögren's syndrome
Discovery of several predictive biomarkers that correlate with disease severity
Implications of findings suggest a need for improved treatment strategies

Implication

Retrospective cohort study uncovers predictive biomarkers for peripheral neuropathies in primary Sjögren's syndrome, indicating need for early assessment.

Discussion

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69b257ec96eeacc4fcec712a https://doi.org/10.1186/s40001-026-04192-4

View Full Paper

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Clinical spectrum, predictive biomarkers, and prognostic implications of peripheral neuropathies in primary Sjögren’s syndrome: a retrospective cohort study

Key Points

Implication

Discussion

Cite This Study

Clinical spectrum, predictive biomarkers, and prognostic implications of peripheral neuropathies in primary Sjögren’s syndrome: a retrospective cohort study

Key Points

Implication

Discussion

Cite This Study

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