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March 12, 2026Open Access

Urban Healthcare Antibiotic Resistance Evaluation Over Two Years in Johannesburg, South Africa: Patient Outcomes

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Authors

MKMandisa KhumaloUniversity of JohannesburgSMSipho MotshegaTshwane University of TechnologyNNNontaba NkotshwaTshwane University of Technology

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Overview

Cross-sectional analysis evaluates antibiotic resistance in urban healthcare, highlighting the need for interventions.

Key Points

  • The study aims to evaluate antibiotic resistance levels in urban healthcare facilities in Johannesburg, South Africa.
  • Cross-sectional analysis of data from patients treated at healthcare facilities in urban Johannesburg.
  • Antibiotic susceptibility testing conducted using the Kirby-Bauer method.
  • Comparison of antibiotic resistance rates between urban and rural areas.
  • Antibiotic resistance rates exceeded 50% for certain bacterial strains in urban settings.
  • Urban healthcare environments show a disproportionate contribution to antibiotic-resistant bacteria.
  • Enhanced surveillance and infection control measures are recommended to mitigate resistance.

Cite This Study

Khumalo et al. (2011) studied this question.

synapsesocial.com/papers/69b2581996eeacc4fcec76a3https://doi.org/10.5281/zenodo.18920326
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adoption of Antibiotic Resistance Screening Kits in Northern Ghanaian Primary Healthcare Facilities: A Perspective from Kenya2010
  2. 2P-893. Comparative Antibiotic Stewardship Practices at Upper-Income versus Lower-Income Hospitals in Southern Malawi2026
  3. 3Urban Migrant Workers' Adherence to Tuberculosis Treatment in Johannesburg, South Africa: A Six-Month Retrospective Analysis2010
  4. 4Prevalence of Antimicrobial Resistance in Klebsiella pneumoniae in the South African Populations: A Systematic Review and Meta‐Analysis of Surveillance Studies2025 · 13 citations
  5. 5Integration and Evaluation of Antimicrobial Resistance Surveillance at Kenyan Primary Healthcare Facilities Over Time2012