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Findings show that radioactive iodine therapy does not improve survival in T4aM0 papillary thyroid carcinoma, suggesting personalized approaches may be better.
RAI therapy does not significantly improve cancer-specific survival in T4aM0 PTC patients after total thyroidectomy. These findings suggest that RAI may not be necessary for this subgroup, advocating for more individualised treatment approaches.
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Li et al. (2026) studied this question.
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