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The study demonstrates a robust Th1-type immune response in humans after vaccination, suggesting effective protection.
This study demonstrates that the cell mediated immune response induced by a single dose of the hRVFV-4s vaccine is characterized by robust, virus-specific Th1-type CD4+ and CD8+ T-cell response. Together with previously reported virus-neutralizing antibody responses, these coordinated immune responses are expected to contribute to vaccine-mediated protection.
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Aregay et al. (2026) studied this question.
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