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March 13, 2026SHILAP Revista de lepidopterologíaOpen Access

Pathogenicity and molecular characterization of cyprinid herpesvirus-2 (CyHV-2) infecting Hypophthalmichthys molitrix in India

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Authors

SMSupratim MallaHSHimadri SahaLGLija Ghosh

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Overview

Investigates the pathogenicity of CyHV-2 in Chinese carps, revealing critical insights for aquaculture management.

Key Points

  • The study aims to investigate the pathogenicity and molecular characteristics of CyHV-2 in Hypophthalmichthys molitrix fish in India.
  • Conducted epidemiological observations and pathology assessments in affected fish.
  • Performed molecular characterization via PCR and sequence analysis of viral DNA.
  • Executed experimental infection trials using various tissue-derived inocula to assess mortality rates.
  • Included bacteriological analysis to explore viral-bacterial interactions.
  • Affected fish showed significant clinical signs, including lethargy and hemorrhages.
  • CyHV-2 was detected in both diseased and healthy fish, indicating potential subclinical infections.
  • Kidney and gill-derived inocula resulted in up to 80% mortality, whereas liver-derived inocula showed only 10% mortality.
  • Aeromonas infections were found concurrent with CyHV-2, suggesting a potential synergistic effect.

Cite This Study

Malla et al. (2026) studied this question.

synapsesocial.com/papers/69b3aaa802a1e69014ccb6fbhttps://doi.org/10.17017/j.fish.1196
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