Quality of Life and Potential Biomarkers in Different Phenotypes of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Key Points

• The aim is to evaluate quality of life and identify potential biomarkers in different chronic rhinosinusitis with nasal polyps phenotypes.
• Used SNOT-22 to assess quality of life in patients with CRSwNP
• Compared phenotypes, specifically N-ERD patients, for quality of life burden
• Conducted biomarker analysis to differentiate inflammatory profiles
• N-ERD patients reported a greater quality of life burden as measured by SNOT-22
• Biomarker analysis indicated distinct inflammation profiles for CRSwNP phenotypes