Systematic review assesses diagnostic features of acral lentiginous melanoma, suggesting improved detection methods.
While the parallel ridge and parallel furrow patterns remain key diagnostic indicators of ALM and benign acral lesions, this systematic review and meta-analysis establishes the additional diagnostic significance of multicomponent and latticelike features. Nearly 20% of ALM lacked the parallel ridge pattern, demonstrating the need for new specific features for melanoma diagnosis. These findings provide evidence-based benchmarks to potentially improve diagnostic accuracy, guide dermoscopy training, and enhance early detection of ALM.
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Okwara et al. (2026) studied this question.
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