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November 10, 2025Clinical and Experimental DermatologyOpen Access

Understanding Acral Lentiginous Melanoma: From Clinic to Guidelines

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Authors

OFOpeoluwa FariyikeNJNicholas A. JohnsonPCPaul Craig

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Overview

Acral lentiginous melanoma shows poorer prognosis with 80.6% survival in affected skin areas, indicating a need for improved diagnosis and treatment.

Key Points

  • This research aims to illuminate the characteristics and management of acral lentiginous melanoma.
  • Review of literature on melanoma subtypes, focusing on acral lentiginous melanoma.
  • Analysis of survival rates and prognostic factors in various demographics.
  • Discussion of treatment modalities including surgery and systemic therapy.
  • Acral lentiginous melanoma is characterized by atypical melanocytes in non-sun-exposed skin areas.
  • The five-year survival rate averages 80.6%, with increased prevalence in non-White populations.
  • Management strategies include wide local excision, radiotherapy, and systemic therapy for advanced cases.

Cite This Study

Fariyike et al. (2025) studied this question.

synapsesocial.com/papers/69253a31c0ce034ddc357893https://doi.org/10.1093/ced/llaf501
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Also Consider

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  1. 1Acral Lentiginous Melanoma: A Review and Diagnostic and Surgical Considerations for the Mohs and Dermatologic Surgeon2026
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  5. 5Management of acral lentiginous melanoma: current updates and future directions2024 · 32 citations