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April 1, 2009Archives of DermatologyOpen Access

Acral Lentiginous Melanoma

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Authors

PBPorcia T. BradfordNational Institutes of HealthAGAlisa M. GoldsteinNational Institutes of HealthMMMary L. McMasterUniversity of North Carolina at Chapel Hill

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Implication

Population-based registry study examines survival and incidence of acral lentiginous melanoma, suggesting poorer outcomes in certain racial groups.

Key Points

  • To examine the incidence and survival patterns of acral lentiginous melanoma (ALM) in the United States.
  • Population-based registry study using SEER Program data from 1986 to 2005
  • 1413 subjects with histologically confirmed ALM cases were analyzed
  • Evaluated incidence rates and survival patterns across various racial groups.
  • Age-adjusted incidence rate of ALM was 1.8 per million person-years
  • 5- and 10-year melanoma-specific survival rates for ALM were 80.3% and 67.5%, significantly lower than overall cutaneous melanoma rates (P < .001)
  • Survival rates varied by race: highest in non-Hispanic whites (82.6% and 69.4%), lower in blacks (77.2% and 71.5%), and lowest in Hispanic whites (72.8% and 57.3%) and Asian/Pacific Islanders (70.2% and 54.1%).

Cite This Study

Bradford et al. (2009) studied this question.

synapsesocial.com/papers/6a02fc8dbc3ffe278e653c13https://doi.org/10.1001/archdermatol.2008.609
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acral cutaneous melanoma in caucasians: clinical features, histopathology and prognosis in 112 patients2000 · 266 citations
  2. 2Survival for Patients With Invasive Cutaneous Melanoma Among Ethnic Groups: The Effects of Socioeconomic Status and Treatment2007 · 178 citations
  3. 3Acral Lentiginous Melanoma1994 · 63 citations
  4. 4Improving Melanoma Classification by Integrating Genetic and Morphologic Features2008 · 384 citations