Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla

Key Points

• This research aims to investigate the connectivity of thalamic subnuclei in individuals with major depressive disorder (MDD).
• Used 7 Tesla MRI for high-resolution imaging of thalamic subnuclei
• Analyzed connectivity patterns with cortical and subcortical regions
• Compared findings between individuals with MDD and healthy controls
• Increased thalamic connectivity observed in individuals with MDD
• Specific subnuclei showed distinct connectivity patterns related to depression
• Findings suggest a link between thalamic subnuclear activity and MDD symptoms