What question did this study set out to answer?

To characterize near-complete HPgV-2 genomes in individuals co-infected with HCV.

Characterization of near-complete human Pegivirus 2 (HPgV-2) genomes in individuals co-infected with hepatitis C virus (HCV) in Cameroon

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Phylogenetic analysis reveals hepatitis C virus co-infection dynamics and diagnostics in individuals from Cameroon.

To characterize near-complete HPgV-2 genomes in individuals co-infected with HCV.
Used nanopore metagenomics to detect HPgV genomes in HCV-infected plasma
Identified six nearly complete HPgV-2 genomes
Conducted phylogenetic analysis to confirm HPgV-2 genotype
Revealed dynamics of co-infection between HPgV-2 and HCV
Highlighted viral diversity among the identified genomes
Supported the potential for improved diagnostics in co-infected patients

Mounchili-Njifon et al. (2026) studied this question.

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