What type of study is this?

This is a Human Clinical Trial study (also classified as: RCT).

What question did this study set out to answer?

This study aims to assess the impact of early saline bolus on outcomes during resuscitation in newborn lambs.

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Randomised trial shows early saline bolus delays ROSC in perinatal lambs, highlighting the need for careful haemodynamic assessment.

This study aims to assess the impact of early saline bolus on outcomes during resuscitation in newborn lambs.
Randomised controlled trial with newborn lambs in cardiac arrest.
Subjects received either epinephrine first or saline bolus first during resuscitation.
Systemic haemodynamics and blood gases were monitored after intervention.
ROSC occurred in 11 out of 11 lambs during saline bolus administration in the epi-first group.
Mean ROSC time was shorter in the epi-first group compared to bolus-first.
No significant changes in fetal heart rate were noted despite blood loss.

Sankaran et al. (2026) studied this question.

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