Correction: Tonon et al. 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway. Cancers 2022, 14, 1630

Q: What type of study is this?

This is a In Vitro Study study.

Federica Tonon; Maja Čemažar; Urška Kamenšek; Cristina Zennaro; Gabriele Pozzato; Sergio Caserta; Flora Ascione; Mario Grassi; Stefano Guido; Cinzia Ferrari; Laura Cansolino; Francesco Trotta; Biljana Grcar Kuzmanov; Giancarlo Forte; Fabiana Martino; Francesca Perrone; Riccardo Bomben; V. Gattei; Nicola Elvassore; Erminio Murano; Nhung Hai Truong; Michael F. Olson; Rossella Farra; Mario Grassi; Barbara Dapas

doi:10.3390/cancers18060922

Key Points

The aim is to investigate how 5-Azacytidine affects hepatocellular carcinoma cells by targeting specific pathways.
In vitro experiments examining cellular behavior of hepatocellular carcinoma cells
In vivo experiments to assess the effects of 5-Azacytidine on tumor growth
Assessment of the miR-139-5p/ROCK2 pathway involvement
5-Azacytidine significantly reduces proliferation of hepatocellular carcinoma cells
5-Azacytidine decreases migration of hepatocellular carcinoma cells
Targeting the miR-139-5p/ROCK2 pathway contributes to these effects.

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Implication

In vitro and in vivo analysis demonstrates 5-Azacytidine reduces proliferation and migration in hepatocellular carcinoma, suggesting new therapeutic pathways.

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Cite This Study

Tonon et al. (2026) studied this question.

synapsesocial.com/papers/69b4ba1818185d8a39802a88 https://doi.org/10.3390/cancers18060922

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Correction: Tonon et al. 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway. Cancers 2022, 14, 1630

Key Points

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Implication

Discussion

Cite This Study

Correction: Tonon et al. 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway. Cancers 2022, 14, 1630

Key Points

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Implication

Discussion

Cite This Study

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