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March 14, 2026Scientific Reports0 citationsOpen Access

Latent profile analysis of kinesiophobia during the out-of-hospital early rehabilitation phase after PCI in patients with CHD

QWQing WenXMXiaorong MaoHWHai-Yan Wu

Key Result

Kinesiophobia in the out-of-hospital early rehabilitation phase of CHD patients undergoing PCI can be categorized into three groups: low (52.1%), medium (41.6%), and high (6.3%) kinesiophobia.

Key Points

  • The aim is to investigate kinesiophobia during early rehabilitation after PCI in CHD patients and classify these profiles using latent profile analysis.
  • Conducted latent profile analysis to identify categories of kinesiophobia.
  • Utilized chi-square tests, Kruskal-Wallis tests, and multinomial logistic regression to determine influencing factors.
  • Surveyed 293 CHD patients in early outpatient rehabilitation post-PCI.
  • Identified three kinesiophobia categories: low exercise avoidance, medium danger perception, and high dysfunction.
  • Age, chronic comorbidities, and polypharmacy were significant factors influencing kinesiophobia profiles.
  • Highlighted the need for individualized intervention strategies based on specific kinesiophobia characteristics.

Study Design

Type

Observational (n=293)

Multicenter

Yes

Structured PICO

P
Population
293 adults with coronary heart disease (CHD) in the out-of-hospital early rehabilitation phase (within 6 months) after successful percutaneous coronary intervention (PCI), mean age 62.31 ± 11.49 years, 77% male, from a tertiary hospital in Sichuan Province, China.
O
Outcome
Kinesiophobia profiles identified via Latent Profile Analysis using the Tampa Scale for Kinesiophobia Heart (TSK-SV Heart) and their influencing factorspatient reported

In patients undergoing early out-of-hospital rehabilitation after PCI, kinesiophobia is highly prevalent (86.7%) and exhibits distinct profiles influenced by age, comorbidities, polypharmacy, and frailty, highlighting the need for individualized psychological interventions.

Limitations

  • Focus primarily on kinesiophobia without broader psychological factors
  • Single-center study may limit generalizability
  • Use of self-reported measures may introduce bias

Abstract

Previous studies have indicated that Kinesiophobia is associated with adherence to exercise rehabilitation. Given the multifaceted impact of Kinesiophobia and the complex diversity of individual characteristics, existing research struggles to identify the distinct features of Kinesiophobia. Latent Profile Analysis (LPA) identifies individuals’ latent traits based on their response patterns to observable measures, grouping individuals with similar symptom profiles into different categories, thereby better distinguishing differences among individuals. However, there is currently a lack of research on the kinesiophobia in the out-of-hospital early rehabilitation phase after Percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD). Therefore, the aim of this study is to investigate kinesiophobia in the out-of-hospital early rehabilitation phase after Percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD), classify it based on latent profile analysis, and explore the related factors of Kinesiophobia in CHD patients across different categories. This study selected coronary heart disease patients who were in the early outpatient rehabilitation stage after receiving PCI treatment at a tertiary hospital as the survey subjects. Latent Profile Analysis (LPA) was employed to fit potential classes of kinesiophobia among these patients. Chi-square tests, Kruskal-Wallis tests, and multinomial logistic regression were utilized to explore the factors influencing different kinesiophobia profiles in these patients. A total of 293 survey subjects were included, the age of the 293 patients was 62.31 ± 11.49 years, Males represent 77% of the total population. The results of potential profile analysis revealed that kinesiophobia in the out-of-hospital early rehabilitation phase of CHD in PCI-treated patients could be divided into three potential categories: the low kinesiophobia-exercise avoidance group (52.1%), the medium kinesiophobia-danger perception group (41.6%), and the high kinesiophobia-dysfunction group (6.3%). The logistic regression analysis results revealed that age, mode of residence, chronic comorbidities, polypharmacy, and debilitation were influential factors for different categories of kinesiophobia in the out-of-hospital early rehabilitation phase of CHD patients undergoing PCI. There is obvious group heterogeneity in kinesiophobia in the out-of-hospital early rehabilitation phaseof CHD patients undergoing PCI, and healthcare professionals should carry out individualized intervention Strategies to reduce the degree of kinesiophobia in patients on the basis of the characteristics and influencing factors of different categories.

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Cite This Study

Wen et al. (2026) conducted an observational in Coronary Heart Disease (n=293). Out-of-hospital early rehabilitation after PCI was evaluated on Categories of kinesiophobia. Kinesiophobia in the out-of-hospital early rehabilitation phase of CHD patients undergoing PCI can be categorized into three groups: low (52.1%), medium (41.6%), and high (6.3%) kinesiophobia.

synapsesocial.com/papers/69b4fb1bb39f7826a300bae1https://doi.org/10.1038/s41598-026-42755-x
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