What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Coronary artery disease post-percutaneous coronary intervention (n=220). Intervention: Home-based cardiac rehabilitation. Primary outcome: Tampa Scale for Kinesiophobia (TSK) scores (R2 46.5%).

What does this research mean for the field?

Kinesiophobia in post-PCI patients is significantly predicted by factors including living alone, clinical symptom severity, and low cardiac rehabilitation knowledge, which interact to drive fear through symptom misinterpretation, cognitive amplification, and behavioral avoidance. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to identify the determinants of kinesiophobia in post-PCI patients and understand their interaction in rehabilitation engagement.

June 24, 2026Frontiers in Cardiovascular MedicineOpen Access

Proposing an explanatory framework based on the fear-avoidance model: a mixed-methods analysis of kinesiophobia in patients after percutaneous coronary intervention in home-based cardiac rehabilitation

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Key result

Clinical and demographic factors plus low rehab knowledge explain ~47% of kinesiophobia variance post-PCI.

R2 46.5%
n=220

Why the study?

What are the determinants of kinesiophobia in patients following percutaneous coronary intervention participating in home-based cardiac rehabilitation?

Population

220 post-PCI patients, mean age 57.85 ± 12.17 years, 77.3% male, 87.3% living with a partner, 69.5% with…

Design

Cross-sectional

Authors

LSL SunNanjing Drum Tower Hospital CNChunlei NieSoutheast University DXDandan XuNanjing Medical University

Discussion

Member takes

Implication

Associations may guide kinesiophobia screening in post-PCI home rehabilitation; leaves open whether targeted interventions improve adherence.

Key Points

This study aims to identify the determinants of kinesiophobia in post-PCI patients and understand their interaction in rehabilitation engagement.
Sequential explanatory mixed-methods design combining a cross-sectional survey of 220 post-PCI patients and semi-structured interviews with high kinesiophobia individuals
Quantitative analysis utilized multiple linear regression to evaluate predictors of kinesiophobia
Qualitative phase involved thematic analysis of interviews with 18 participants showing high kinesiophobia.
Living alone and lower cardiac rehabilitation knowledge scores significantly predicted higher kinesiophobia levels (β = 0.17, 95% CI: 1.53–6.45; β = -0.43, 95% CI: -0.24–0.15)
The combined factors explained 46.5% of variance in TSK scores
Four key themes identified in qualitative analysis reveal the complexity of kinesiophobia, including symptom misinterpretation and knowledge gaps.

Study Design

Type

Cross-Sectional (n=220)

Multicenter

Structured PICO

What are the determinants of kinesiophobia in patients following percutaneous coronary intervention participating in home-based cardiac rehabilitation?

Population

220 post-PCI patients, mean age 57.85 ± 12.17 years, 77.3% male, 87.3% living with a partner, 69.5% with comorbid chronic conditions.

Intervention

Home-based cardiac rehabilitation

Outcome

Determinants of kinesiophobia (Tampa Scale for Kinesiophobia scores)patient reported

Main Result

Effect estimate: R2 46.5%

Kinesiophobia in post-PCI patients is driven by symptom misinterpretation, cognitive/environmental factors, and knowledge deficits, suggesting targeted education may improve cardiac rehabilitation engagement.

Limitations

Cross-sectional quantitative design and qualitative interviews limit causal inference.
Limited sample size may affect generalizability.
Unmeasured psychological and environmental factors likely contribute to the phenomenon.
Single-country setting necessitates caution when extrapolating findings to other healthcare systems and cultural contexts.

Cite This Study

Sun et al. (2026) conducted a cross-sectional in Coronary artery disease post-percutaneous coronary intervention (n=220). Home-based cardiac rehabilitation was evaluated on Tampa Scale for Kinesiophobia (TSK) scores (R2 46.5%). Living alone, urban residence, previous PCI history, comorbidities, clinical symptom severity, and lower cardiac rehabilitation knowledge scores collectively explained 46.5% of the variance in kinesiophobia levels among post-PCI patients.

synapsesocial.com/papers/6a3c2356d15afadd906f9ffc https://doi.org/10.3389/fcvm.2026.1819126

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June 24, 2026Frontiers in Cardiovascular MedicineOpen Access

Proposing an explanatory framework based on the fear-avoidance model: a mixed-methods analysis of kinesiophobia in patients after percutaneous coronary intervention in home-based cardiac rehabilitation

View Full Paper

Ask AI

Bookmark

Key result

Clinical and demographic factors plus low rehab knowledge explain ~47% of kinesiophobia variance post-PCI.

R2 46.5%
n=220

Why the study?

What are the determinants of kinesiophobia in patients following percutaneous coronary intervention participating in home-based cardiac rehabilitation?

Population

220 post-PCI patients, mean age 57.85 ± 12.17 years, 77.3% male, 87.3% living with a partner, 69.5% with…

Design

Cross-sectional

Authors

LSL SunNanjing Drum Tower Hospital CNChunlei NieSoutheast University DXDandan XuNanjing Medical University

Discussion

Member takes

Implication

Associations may guide kinesiophobia screening in post-PCI home rehabilitation; leaves open whether targeted interventions improve adherence.

Key Points

This study aims to identify the determinants of kinesiophobia in post-PCI patients and understand their interaction in rehabilitation engagement.
Sequential explanatory mixed-methods design combining a cross-sectional survey of 220 post-PCI patients and semi-structured interviews with high kinesiophobia individuals
Quantitative analysis utilized multiple linear regression to evaluate predictors of kinesiophobia
Qualitative phase involved thematic analysis of interviews with 18 participants showing high kinesiophobia.
Living alone and lower cardiac rehabilitation knowledge scores significantly predicted higher kinesiophobia levels (β = 0.17, 95% CI: 1.53–6.45; β = -0.43, 95% CI: -0.24–0.15)
The combined factors explained 46.5% of variance in TSK scores
Four key themes identified in qualitative analysis reveal the complexity of kinesiophobia, including symptom misinterpretation and knowledge gaps.

Study Design

Type

Cross-Sectional (n=220)

Multicenter

Structured PICO

What are the determinants of kinesiophobia in patients following percutaneous coronary intervention participating in home-based cardiac rehabilitation?

Population

220 post-PCI patients, mean age 57.85 ± 12.17 years, 77.3% male, 87.3% living with a partner, 69.5% with comorbid chronic conditions.

Intervention

Home-based cardiac rehabilitation

Outcome

Determinants of kinesiophobia (Tampa Scale for Kinesiophobia scores)patient reported

Main Result

Effect estimate: R2 46.5%

Limitations

Cross-sectional quantitative design and qualitative interviews limit causal inference.
Limited sample size may affect generalizability.
Unmeasured psychological and environmental factors likely contribute to the phenomenon.
Single-country setting necessitates caution when extrapolating findings to other healthcare systems and cultural contexts.

Cite This Study

synapsesocial.com/papers/6a3c2356d15afadd906f9ffc https://doi.org/10.3389/fcvm.2026.1819126

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