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March 14, 2026Natural Product CommunicationsOpen Access

Antitumor Effects of Ganoderma lucidum polysaccharides and their Clinical Applications: An Updated Review

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Authors

MWMengdi WangChongqing University of Posts and TelecommunicationsXGXia GuoHebei University of Economics and BusinessJCJiale ChenZhejiang Sci-Tech University

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Implication

An updated review demonstrates the anti-cancer potential of Ganoderma lucidum polysaccharides in cancer therapy, suggesting improved outcomes for patients.

Key Points

  • To systematically review the antitumor mechanisms and clinical applications of Ganoderma lucidum polysaccharides (GLPs) in cancer treatment.
  • Review of current literature on GLPs and their effects on tumor cells.
  • Evaluation of signaling pathways involved in GLPs' mechanisms.
  • Analysis of GLPs' role in modulating immune responses in cancer.
  • GLPs induce tumor cell death via multiple apoptosis pathways.
  • GLPs enhance immune cell functions, improving the tumor immune microenvironment.
  • Clinical applications of GLPs as adjuvant therapies show potential for improved patient outcomes.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69b4fb8db39f7826a300bcdchttps://doi.org/10.1177/1934578x261429763
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