What question did this study set out to answer?

To evaluate the impact of targeted preoperative nutritional support on postoperative outcomes in malnourished colorectal cancer patients compared to well-nourished patients.

March 15, 2026Annals of Surgical OncologyOpen Access

Targeted Preoperative Nutritional Support within an Enhanced Recovery After Surgery Program for Malnourished Colorectal Cancer Patients: Postoperative Outcomes Comparable to Well-Nourished Patients in a Prospective Single-Center Cohort

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Authors

NVNuria Valdés LDLucia DíazHospital Universitario De Cabueñes PTPatricia TorricoHospital Universitario De Cabueñes

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Implication

Prospective cohort shows nutritional intervention aids postoperative outcomes in malnourished colorectal cancer patients, implying comparable recovery to well-nourished counterparts.

Key Points

To evaluate the impact of targeted preoperative nutritional support on postoperative outcomes in malnourished colorectal cancer patients compared to well-nourished patients.
Conducted a prospective observational cohort study in an ERAS-certified hospital.
Screened 187 patients for malnutrition using specific criteria before elective colorectal resection.
Provided individualized nutritional counseling and oral supplements preoperatively as per ESPEN guidelines.
No significant difference in postoperative complication rates between malnourished (38.1%) and well-nourished (31.7%) patients (P = 0.276).
Median length of stay was similar (8 days for malnourished vs. 7 days for well-nourished; P = 0.36).
Malnutrition was not independently associated with complications or prolonged length of stay in multivariable analysis.

Cite This Study

Valdés et al. (2026) studied this question.

synapsesocial.com/papers/69b5ff3b83145bc643d1b565 https://doi.org/10.1245/s10434-025-18778-5

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Implication

Prospective cohort shows nutritional intervention aids postoperative outcomes in malnourished colorectal cancer patients, implying comparable recovery to well-nourished counterparts.

Targeted Preoperative Nutritional Support within an Enhanced Recovery After Surgery Program for Malnourished Colorectal Cancer Patients: Postoperative Outcomes Comparable to Well-Nourished Patients in a Prospective Single-Center Cohort

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Key Points

Cite This Study

Targeted Preoperative Nutritional Support within an Enhanced Recovery After Surgery Program for Malnourished Colorectal Cancer Patients: Postoperative Outcomes Comparable to Well-Nourished Patients in a Prospective Single-Center Cohort

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Implication

Key Points

Cite This Study

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