In Vivo Hyperspectral Imaging of Vasogenic Edema and Cortical Oxygenation in Meningiomas: A Subgroup Interim Analysis of a Prospective Study

Key Points

• This research aims to analyze the relationship between vasogenic edema and cortical oxygenation in meningiomas using hyperspectral imaging.
• Conducted a subgroup interim analysis in a prospective study design.
• Utilized in vivo hyperspectral imaging as the main investigative tool.
• Focused on the assessment of cerebral tissue characteristics during surgery.
• Found impaired cortical oxygenation associated with vasogenic edema in meningiomas.
• Larger vasogenic edemas paradoxically showed higher StO2 levels, indicating compensatory mechanisms.
• Strong tumor enhancement was correlated with local hypoxia.