Preoperative tumor and edema volumes as predictors of ischemia and morbidity after intracranial meningioma surgery.

Background: Ischemic complications remain a significant risk indicator of morbidity after meningioma surgery. While tumor size and extent of resection (EOR) are recognized risk factors, the prognostic impact of peritumoral brain edema volume (PTBEV) is not fully established. This study investigated whether preoperative tumor volume (TV) and PTBEV independently predict postoperative ischemia and neurological morbidity. Methods: value < .05 was considered significant. Results: = .017). Conclusion: Preoperative tumor and edema volumes are independent predictors of postoperative ischemia. Even modest ischemic lesions (>2 cm³) can cause clinically relevant morbidity. Volumetric biomarkers should be integrated into surgical planning, with prospective multicenter validation warranted.