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To assess the impact of antimicrobial susceptibility reporting changes on clinical outcomes in BCC bacteremia.

March 15, 2026Journal of Clinical Infectious Disease SocietyOpen Access

Lessons Learned from Patients with Bacteremia Caused by Burkholderia cepacia Complex: A 5-year Experience from a Single Center

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To assess the impact of antimicrobial susceptibility reporting changes on clinical outcomes in BCC bacteremia.
Retrospective analysis of 128 blood culture isolates from a single center
Minimum inhibitory concentration testing using broth microdilution methods
Comparison of susceptibility interpretation before and after the 2025 updates to clinical breakpoints
73.6% clinical cure rate and 69.1% microbiological cure rate achieved
14.3% and 23.1% mortality at days 14 and 28, respectively
Septic shock identified as the only independent predictor of 28-day mortality with odds ratio 4.223

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Retrospective study reveals high mortality in BCC bacteremia, suggesting further evaluation of antimicrobial therapy strategies.

Prayag et al. (2026) studied this question.

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