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March 12, 2026Journal of Nuclear MedicineOpen Access

Is CXCR4 Theranostics in Oncologic, Cardiovascular, and Inflammatory Diseases Really Happening?

Philipp E. Hartrampf Rudolf Werner Takahiro Higuchi Margret Schottelius Andreas K. Buck

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Key Points

The research aims to explore the role of CXCR4 in oncologic, cardiovascular, and inflammatory diseases, focusing on theranostic applications.
Analysis of CXCR4's functions in various biological processes
Review of current interventions targeting CXCR4
Evaluation of CXCR4 as a biomarker for disease management
CXCR4 is implicated in tumor growth and metastasis, indicating its significance in cancer
The receptor plays a crucial role in cardiovascular and inflammatory processes
Potential for CXCR4-targeted therapies is highlighted, suggesting new treatment avenues

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Implication

Investigates the role of CXCR4 in various diseases, suggesting potential therapeutic implications.

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Cite This Study

Hartrampf et al. (2026) studied this question.

synapsesocial.com/papers/69b64c67b42794e3e660db43 https://doi.org/10.2967/jnumed.125.271153

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