What question did this study set out to answer?

This research aims to evaluate the antioxidant potential and cytotoxicity of bioactive metabolites extracted from edible mushrooms.

Bioactive metabolites from edible fungi: evaluation of antioxidant potential and cytotoxicity on human cell lines

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Analysis reveals antioxidant potential and cytotoxic effects of wild mushrooms on human cell lines, suggesting further pharmacological investigation.

This research aims to evaluate the antioxidant potential and cytotoxicity of bioactive metabolites extracted from edible mushrooms.
Extracted bioactive compounds from six edible wild mushrooms using methanol.
Screened for flavonoids, phenols, and anthraquinones in the extracts.
Measured antioxidant activity using DPPH and ABTS assays.
Conducted toxicity assays on Artemia salina to determine LD50 values.
Tested cytotoxic effects on various cancer cell lines.
Highest flavonoid and phenol content found in Amanita caesarea.
Laccaria laccata exhibited the highest antioxidant activity in the ABTS assay.
LD50 values for the fungi ranged from 27.6 to 118.6 µg/mL, indicating variable toxicity.
Clitocybe gibba demonstrated cytotoxic activity against multiple cancer cell lines.

Malacara-Marquez et al. (2026) studied this question.

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Analysis reveals antioxidant potential and cytotoxic effects of wild mushrooms on human cell lines, suggesting further pharmacological investigation.