What does this research mean for the field?

Etoricoxib provides effective preemptive analgesia, reducing postoperative pain and improving functional recovery after third molar surgery. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to evaluate the efficacy of the COX-2 inhibitor etoricoxib for preemptive analgesia in third molar surgery.

March 16, 2026Journal of Oral and Maxillofacial SurgeryOpen Access

Efficacy of Highly Selective COX-2 Inhibitors in Preemptive Analgesia for Third Molar Surgery: A Meta-analysis

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This research aims to evaluate the efficacy of the COX-2 inhibitor etoricoxib for preemptive analgesia in third molar surgery.
Conducted a meta-analysis of existing studies on etoricoxib and analgesia post third molar extraction.
Analyzed pain levels and functional recovery in patients receiving etoricoxib preemptively.
Compared outcomes between patients using etoricoxib and those who did not.
Etoricoxib significantly reduced postoperative pain compared to control treatments.
Patients receiving etoricoxib reported better functional recovery after surgery.

Implication

Meta-analysis measures the effect of etoricoxib on pain and recovery after third molar surgery, indicating potential benefits.

Abstract

Background: Though postoperative acute pain following third molar extraction impairs patient satisfaction and increases healthcare costs, evidence regarding the efficacy of the highly selective cyclooxygenase-2 (COX-2) inhibitor etoricoxib for preemptive analgesia in this setting remains unclear. Purpose:The purpose of this study was to measure the association of etoricoxib preemptive analgesia on pain and functional recovery after third molar surgery.

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69b79dce8166e15b153aaffd https://doi.org/10.1016/j.joms.2026.03.007

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Implication

Meta-analysis measures the effect of etoricoxib on pain and recovery after third molar surgery, indicating potential benefits.

Efficacy of Highly Selective COX-2 Inhibitors in Preemptive Analgesia for Third Molar Surgery: A Meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Efficacy of Highly Selective COX-2 Inhibitors in Preemptive Analgesia for Third Molar Surgery: A Meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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