Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 16, 2026

The potential antileishmanial activity of some Sudanese medicinal plants

View Full Paper
Ask AI
Bookmark
Share

Authors

ATAhmed El TahirAIAdil IbrahimUniversity of KhartoumGSGwiria M.H. SattiUniversity of Khartoum

Discussion

Loading...

Member takes

Implication

Examination unveils antileishmanial activity in selected Sudanese plants, suggesting potential therapeutic uses.

Key Points

  • The study aims to evaluate the antileishmanial properties of various Sudanese medicinal plants against Leishmania major.
  • Evaluated crude methanol extracts from eight plant species.
  • Determined in vitro antileishmanial activity using IC50 values.
  • Conducted liquid-liquid partitioning and phytochemical analysis of effective extracts.
  • Three plants demonstrated significant antileishmanial effects with IC50 values of 11.5, 55, and 78 μg/mL.
  • M. senegalensis extracts showed the highest activity at 5 μg/mL.
  • Phytochemical analysis indicated the presence of terpenoids and minimal toxic effects on lymphocytes.

Cite This Study

Tahir et al. (1998) studied this question.

synapsesocial.com/papers/69b79e398166e15b153ab488https://doi.org/10.1002/(sici)1099-1573(199812)12:8<576::aid-ptr354>3.0.co;2-%23
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antileishmanial potential of medicinal plants: A global systematic and meta-analytic review of in vitro studies2026
  2. 2Antileishmanial Activity of Bioactive Compounds Obtained from Azadirachta indica and Cnidoscolus spp.: Systematic Review2026
  3. 3Study the effect of phenolic compounds extracted from some wild Iraqi plants as anti-leishmaniasis in vitro2025
  4. 4In vitro antileishmanial activities of hydro-methanolic crude extracts and solvent fractions of Clematis simensis fresen leaf, and Euphorbia abyssinica latex2024 · 3 citations
  5. 5Harnessing nature: a systematic exploration of <i>in vitro</i> antileishmanial and antihuman African trypanosomal properties in traditional medicinal plants and their active principles.2026