Retrospective chart review shows decreased urate levels in gout patients after starting dialysis, suggesting dose reevaluation is necessary.
Serum urate concentrations declined after starting dialysis with unchanged allopurinol dosing, suggesting dialysis independently contributes to urate reduction. These findings support re-evaluating allopurinol dose in patients after commencing dialysis, including de-prescribing allopurinol in those who consistently achieve target urate concentrations.
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Kamel et al. (2026) studied this question.
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