What does this research mean for the field?

Moderate alcohol consumption is associated with higher HDL-c levels and lower odds of low HDL-c, particularly among individuals without obesity. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to explore how obesity influences the relationship between alcohol consumption and HDL-c levels.

March 16, 2026LipidsOpen Access

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

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Authors

LCLarissa Esthefani Barros CirinoUniversidade Federal do Amazonas DZDivanei Zaniqueli OEOscar Geovanny Enriquez‐MartinezUniversidade Federal do Espírito Santo

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Implication

Cross-sectional analysis assesses alcohol's impact on HDL-c in obesity, suggesting varying effects between groups.

Key Points

This study aims to explore how obesity influences the relationship between alcohol consumption and HDL-c levels.
Cross-sectional analysis using data from the Baependi Heart Study
Included 2345 participants aged 18-100 years
Categorized alcohol intake based on weekly ethanol consumption
Measured HDL-c levels through standard biochemical methods
No significant differences in total cholesterol, LDL-c, or triacylglycerols across alcohol consumption groups
Higher HDL-c/LDL-c ratio among male moderate consumers
Significant interaction between obesity and moderate alcohol consumption (β = 0.90, p = 0.015)
Moderate alcohol consumers had significantly higher HDL-c levels compared to abstainers among nonobese individuals
Moderate alcohol intake linked to a 65% reduction in low HDL-c odds in women and 66% in men within nonobese participants

Cite This Study

Cirino et al. (2026) studied this question.

synapsesocial.com/papers/69b79ea18166e15b153ac330 https://doi.org/10.1002/lipd.70050

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The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

Discussion

Member takes

Implication

Key Points

Cite This Study

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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