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To present a case of mucocutaneous histoplasmosis in a patient with an autoimmune disease and discuss diagnostic and therapeutic considerations.

Mucocutaneous Histoplasmosis in a Patient With Autoimmune Disease: A Case Report

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To present a case of mucocutaneous histoplasmosis in a patient with an autoimmune disease and discuss diagnostic and therapeutic considerations.
Reported clinical case of a 51-year-old woman with autoimmune disease and mucocutaneous lesions.
Conducted imaging with contrast-enhanced CT of the paranasal sinuses.
Performed incisional biopsy and mycological examination to confirm diagnosis.
Administered trimethoprim-sulfamethoxazole and amphotericin B lipid complex as treatment.
Diagnosed mucocutaneous histoplasmosis based on biopsy and mycological confirmation.
Imaging showed soft-tissue thickening and bony erosions in nasal regions.
Patient responded positively to antifungal therapy after initial antibiotic treatments.

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Case report reveals mucocutaneous histoplasmosis diagnosis in autoimmune disease, highlighting diagnostic challenges.

Avelino et al. (2026) studied this question.

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