Cutaneous histoplasmosis in a patient undergoing chemotherapy: A case report

This is a 63 year old patient, history of diagnosed vulvar neoplasm, received 7 courses of chemotherapy. Follow-up for Hodgkin's lymphoma refractory to several lines of treatment. The history of the disease dates back 3 days before her admission with the onset of fever syndrome at 39° with a dry cough evolving in a context of preservation of the general condition, which motivates her consultation in the emergency room. She presents two swellings at the level of the foot and the hand budding keratotic, indurated well limited. These two lesions are biopsied. Histoplasmosis is retained as a diagnosis. The infection is caused by the inhalation of spores suspended in the air of Histoplasma capsulatum, a dimorphic saprophytic fungus present in soil contaminated by bird or bat droppings. Occurs as filamentous in the environment and in vitro, and yeast-like in tissues at 2-4 μm in size, usually associated with immunocompromised patients, special stains for Grocott and PAS highlight the germ.