What question did this study set out to answer?

This case aims to highlight the challenges in diagnosing acute pulmonary histoplasmosis in immunocompetent patients.

May 20, 2026American Journal of Respiratory and Critical Care Medicine

B72-14 Acute Pulmonary Histoplasmosis Mimicking Malignancy in an Immunocompetent Woman

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This case aims to highlight the challenges in diagnosing acute pulmonary histoplasmosis in immunocompetent patients.
Case report of a 40-year-old woman with persistent fever and pulmonary symptoms.
Diagnostic imaging included CT angiogram and repeat CT scans.
Bronchoscopy with bronchoalveolar lavage (BAL) and serological testing for Histoplasma.
Initial imaging showed a pleural-based nodule and enlarged lymph nodes.
Histoplasma antibody testing resulted in a weakly positive mycelial titer (1:4).
Empiric antifungal treatment led to recovery and resolution of pulmonary opacities.

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Implication

Case presentation reveals acute pulmonary histoplasmosis mimicking malignancy in an immunocompetent woman, suggesting early antifungal treatment is crucial.

Cite This Study

Orozco et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5000f03e14405aa9b888 https://doi.org/10.1093/ajrccm/aamag162.4303

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Implication

Case presentation reveals acute pulmonary histoplasmosis mimicking malignancy in an immunocompetent woman, suggesting early antifungal treatment is crucial.

B72-14 Acute Pulmonary Histoplasmosis Mimicking Malignancy in an Immunocompetent Woman

Key Points

Discussion

Implication

Cite This Study

B72-14 Acute Pulmonary Histoplasmosis Mimicking Malignancy in an Immunocompetent Woman

Key Points

Discussion

Implication

Cite This Study

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