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March 17, 2026The Brazilian Journal of Infectious DiseasesOpen Access

Impedimetric Immunosensor for Detection of Peptidorhamnomannan (Prm) From Sporothrix Brasiliensis

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Authors

JSJúlio César SilvaUniversidade Federal de GoiásINIsac Nilton Sousa NevesUniversidade Federal de GoiásMPMarx Osório Araújo PereiraUniversidade Federal de Goiás

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Implication

Impedimetric immunosensor detects peptidorhamnomannan in Sporothrix brasiliensis, suggesting an improved diagnostic method.

Key Points

  • The study aims to develop a sensitive and selective impedimetric immunosensor for detecting peptidorhamnomannan in Sporothrix brasiliensis.
  • Developed an impedimetric immunosensor using IgY antibodies for PRM detection.
  • Activated a glassy carbon electrode using chronoamperometry.
  • Added antibody and casein suspensions to form a thin film on the electrode.
  • Conducted rinsing steps to eliminate unbound materials.
  • Performed electrochemical tests to assess binding and selectivity of the immunosensor.
  • The immunosensor showed a strong linear response (r² = 0.9983) for detecting PRM.
  • Indicated successful binding between PRM and anti-PRM IgY antibodies.
  • Demonstrated potential as an efficient alternative to traditional diagnostic methods for sporotrichosis.

Cite This Study

Silva et al. (2026) studied this question.

synapsesocial.com/papers/69b8ef12deb47d591b8c5261https://doi.org/10.1016/j.bjid.2026.105206
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