What question did this study set out to answer?

The aim is to identify and characterize the HLA-B*35:01:01:91 allele in a specific donor population.

March 18, 2026HLA

The Novel HLA‐B*35:01:01:91 Allele Identified in a Greek Haematopoietic Stem Cell Donor

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The aim is to identify and characterize the HLA-B*35:01:01:91 allele in a specific donor population.
Identification of HLA allele through genetic testing
Comparison with known HLA alleles
Analysis of nucleotide substitutions
Characterized HLA-B*35:01:01:91 allele
Distinguished from HLA-B*35:01:01:02 by a single nucleotide substitution

Researchers identify a new allele in human leukocyte antigen among stem cell donors, suggesting genetic diversity in tissue matching.

The HLA‐B*35:01:01:91 allele differs from HLA‐B*35:01:01:02 by a single nucleotide substitution in intron 3.

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Kouniaki et al. (2026) studied this question.

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Researchers identify a new allele in human leukocyte antigen among stem cell donors, suggesting genetic diversity in tissue matching.

The HLA‐B*35:01:01:91 allele differs from HLA‐B*35:01:01:02 by a single nucleotide substitution in intron 3.