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March 18, 2026European Respiratory Journal

Persistent wheezing after bronchiolitis: 5 years of follow up

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Authors

MFMarianna FerraraSapienza University of RomeGCGiulia CangianoUniversity of BernANAmbra NicolaiUniversity of Campania "Luigi Vanvitelli"

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Overview

Long-term follow-up reveals risk factors for persistent wheezing in infants after bronchiolitis, indicating the importance of early identification.

Key Points

  • The aim is to identify risk factors for persistent wheezing five years after a bronchiolitis diagnosis.
  • Enrolled 179 infants hospitalized for bronchiolitis from 2004-2007
  • Collected demographic and clinical data from medical files and parental interviews
  • Conducted lung function tests and skin prick tests on 60 children five years post-bronchiolitis
  • 62.6% of families responded to follow-up interviews
  • 35 children never wheezed, while 30 had wheezing episodes each year for five years
  • Higher eosinophil counts were found in children with persistent wheezing compared to non-wheezing peers
  • 80% of infants with rhinovirus bronchiolitis had persistent wheezing, compared to 34.8% with respiratory syncytial virus
  • 73.3% of persistent wheezing children were born via cesarean section

Cite This Study

Ferrara et al. (2013) studied this question.

synapsesocial.com/papers/69ba422e4e9516ffd37a23b9https://doi.org/10.1183/13993003/erj.42.suppl_57.p4322
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk factors for recurrent wheezing following bronchiolitis: 3 yrs of follow-up2011
  2. 2Risk factors for recurrent wheezing after infant bronchiolitis: a 6-year single-centre follow up study in China2025
  3. 3A60-09 Rhinovirus-related Bronchiolitis Is Associated With Atopic Background and Recurrent Wheezing in Infants2026
  4. 4CLINICAL PROFILE AND RISK FACTORS FOR RECURRENT WHEEZING IN CHILDREN UNDER FIVE YEARS OF AGE2026
  5. 5RECURRENT WHEEZING IN CHILDREN: CLINICAL CHARACTERIZATION AND RISK FACTORS BEFORE 5 YEARS OF AGE2025