What question did this study set out to answer?

The study aims to investigate the genomic and phenotypic traits of Bacillus cereus strain IM8 from a glacier.

March 18, 2026Microbiology Resource Announcements0 citationsOpen Access

Whole-genome sequence and phenotypic characteristics of Bacillus cereus strain IM8 isolated from the Upper Fremont Glacier in Wyoming

TCTyler Chandross-Cohen MEMira Ebersole NRNazeerah Abdul Rahman

Key Points

The study aims to investigate the genomic and phenotypic traits of Bacillus cereus strain IM8 from a glacier.
Isolated Bacillus cereus strain IM8 from an ice core sample.
Conducted whole-genome sequencing to analyze genetic identity.
Performed phenotypic characterization focusing on cytotoxic effects and antibiotic resistance.
The strain shows 97.52% average nucleotide identity with B. cereus sensu stricto.
Demonstrated high cytotoxicity towards Caco-2 human intestinal epithelial cells.
Exhibited resistance to ampicillin, suggesting potential pathogenicity.

Abstract

ABSTRACT Bacillus cereus strain IM8 isolated from an ice core of the Upper Fremont Glacier in Wyoming showed 97.52% average nucleotide identity with B. cereus sensu stricto , a lineage typically not associated with psychrotolerance. Phenotypic characterization highlighted high cytotoxicity toward human intestinal epithelial Caco-2 cells and resistance to ampicillin.

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