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March 18, 2026JACC. Clinical electrophysiologyOpen Access

Clinical Characteristics and Outcomes of Patients With Biventricular and Left-Dominant Arrhythmogenic Cardiomyopathy With Ring-like Late Gadolinium Enhancement Pattern

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Key result

Ring-like LGE on CMR identifies arrhythmogenic cardiomyopathy with LV involvement.

Why the study?

The clinical characteristics and prognostic significance of the ring-like pattern of late gadolinium enhancement on CMR in arrhythmogenic cardiomyopathy with LV involvement remain to be clarified.

Does the ring-like late gadolinium enhancement (RL-LGE) pattern on CMR predict clinical outcomes in patients with biventricular and left-dominant arrhythmogenic cardiomyopathy?

Population

Patients with biventricular and left-dominant arrhythmogenic cardiomyopathy (ACM)

Authors

NMNicolò MartiniElectrophysiologyRPRaimondo PittorruUniversity of PaduaRCRudi CeleghinUniversity of Padua

Discussion

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Overview

RL-LGE on CMR was associated with adverse outcomes in biventricular/left-dominant ACM; hypothesis-generating and requires prospective validation before routine adoption.

Key Points

  • This research aims to clarify the clinical features and prognostic implications of the RL-LGE pattern in ACM.
  • Utilized cardiac magnetic resonance imaging to assess late gadolinium enhancement patterns.
  • Analyzed clinical characteristics of patients with biventricular and left-dominant ACM.
  • Evaluated prognostic significance based on clinical outcomes.
  • Identified distinct clinical characteristics associated with the RL-LGE pattern.
  • Suggests possible prognostic implications for patients with left ventricular involvement.

Structured PICO

Does the ring-like late gadolinium enhancement (RL-LGE) pattern on CMR predict clinical outcomes in patients with biventricular and left-dominant arrhythmogenic cardiomyopathy?

P
Population
Patients with biventricular and left-dominant arrhythmogenic cardiomyopathy (ACM)
I
Intervention
Ring-like late gadolinium enhancement (RL-LGE) pattern on cardiac magnetic resonance (CMR)
O
Outcome
Clinical characteristics and outcomes (prognostic significance)

Cite This Study

Martini et al. (2026) studied this question. Ring-like late gadolinium enhancement on cardiac magnetic resonance is a proposed distinctive imaging marker of arrhythmogenic cardiomyopathy with left ventricular involvement.

synapsesocial.com/papers/69ba43cb4e9516ffd37a5673https://doi.org/10.1016/j.jacep.2026.02.019
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Also Consider

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  1. 1Late gadolinium enhancement distribution patterns in non-ischaemic dilated cardiomyopathy: genotype–phenotype correlation2023 · 66 citations
  2. 2Improved Risk Stratification for Ventricular Arrhythmias and Sudden Death in Patients With Nonischemic Dilated Cardiomyopathy2021 · 185 citations
  3. 3Natural History of Arrhythmogenic Cardiomyopathy2020 · 49 citations
  4. 4Arrhythmogenic right ventricular cardiomyopathy: evaluation of the current diagnostic criteria and differential diagnosis2019 · 367 citations
  5. 5Risk Stratification in Nonischemic Dilated Cardiomyopathy Using CMR Imaging2024 · 48 citations