Application of intramolecular Diels-Alder reaction shows synthesis of acids in benzo-cyclofuroisoindoles, indicating synthetic utility and limitations.
Furylallylamines, readily accessible from the corresponding furylacroleines, react with maleic, citraconic and trifluoromethylmaleic anhydrides to form acids with a furo[2,3-f]isoindole core.The reaction sequence involves two successive steps: the acylation of...
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Yakovleva et al. (2025) studied this question.
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