What question did this study set out to answer?

To describe the morphological characteristics, echocardiographic diagnostic criteria, and clinical complications associated with isolated noncompaction of the left ventricular myocardium.

August 1, 1990CirculationOpen Access

Isolated noncompaction of left ventricular myocardium. A study of eight cases.

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Population

Patients with isolated noncompaction of left ventricular myocardium (ages 11 months to 22.5 years)

Comparison

Echocardiographic and morphological assessment vs Normal control subjects

Design

Case_series

Follow-up

up to 5 years

Authors

TCThomas K. ChinUniversity of Central Florida JPJoseph K. PerloffAdult Congenital Heart Disease RWRoberta G. WilliamsPediatric / Congenital Cardiology

Discussion

Member takes

Implication

Echocardiographic quantification may aid noncompaction diagnosis; leaves open validation in larger prospective cohorts.

Key Points

To describe the morphological characteristics, echocardiographic diagnostic criteria, and clinical complications associated with isolated noncompaction of the left ventricular myocardium.
Evaluated 8 patients (aged 11 months to 22.5 years; follow-up up to 5 years), including 3 postmortem necropsy examinations.
Measured intertrabecular recess depth using a quantitative echocardiographic X-to-Y ratio compared against normal control subjects.
The echocardiographic X-to-Y ratio of intertrabecular recess depth was significantly increased compared with normal control subjects (p < 0.001).
Major clinical findings included depressed left ventricular systolic function in 5 patients, ventricular arrhythmias in 5, systemic embolization in 3, facial dysmorphism in 3, and familial recurrence in 4.

Structured PICO

Population

Patients with isolated noncompaction of left ventricular myocardium (ages 11 months to 22.5 years)

Intervention

Echocardiographic and morphological assessment

Comparator

Normal control subjects

Outcome

Depths of intertrabecular recesses (assessed by quantitative echocardiographic X-to-Y ratio) and clinical manifestationssurrogate

Isolated noncompaction of left ventricular myocardium is a rare disorder with a high incidence of cardiovascular complications that can be reliably identified by two-dimensional echocardiography.

Cite This Study

Chin et al. (1990) studied this question.

synapsesocial.com/papers/69bd7133133ce59d3bc7e20c https://doi.org/10.1161/01.cir.82.2.507

Topics

Congenital heart disease adults Echocardiography

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Isolated noncompaction of left ventricular myocardium. A study of eight cases.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Isolated noncompaction of left ventricular myocardium. A study of eight cases.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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