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March 21, 2026American Journal of Case ReportsOpen Access

A 68-Year-Old Man With Neutrophil-Rich Hepatoid Adenocarcinoma of the Gallbladder

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Authors

MCMingxia ChenShenzhen UniversityFKFanhong KongYantaishan HospitalMWMin WangYantaishan Hospital

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Implication

Case report reveals aggressive neutrophil-rich hepatoid adenocarcinoma in a 68-year-old man, indicating critical histopathological confirmation.

Key Points

  • To discuss the rare presentation and aggressive nature of neutrophil-rich hepatoid adenocarcinoma of the gallbladder.
  • Case report of a 68-year-old man with symptoms including abdominal pain and jaundice.
  • Computed tomography (CT) scans identified a malignant gallbladder tumor.
  • Histological and immunohistochemical analyses confirmed the diagnosis.
  • Cholecystectomy and resection of intra-abdominal metastases were performed.
  • Histopathological examination revealed similar features in both primary tumor and metastases.
  • The diagnosis of neutrophil-rich hepatoid adenocarcinoma was confirmed.
  • Histopathological features showed neutrophilic infiltration in both the primary and metastatic tumors.
  • Immunohistochemistry demonstrated positive HepPar-1 staining in the tumor cells.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69be35166e48c4981c6732bbhttps://doi.org/10.12659/ajcr.950825
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