Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 18, 2025Frontiers in OncologyOpen Access

Pancreatic hepatoid adenocarcinoma with neuroendocrine differentiation and elevated AFP: a case report

View Full Paper
Ask AI
Bookmark
Share

Authors

ZYZhenqing YangTLTing LiXZXiaowei Zhang

Discussion

Loading...

Member takes

Overview

Case report reveals elevated AFP associations in pancreatic hepatoid adenocarcinoma, suggesting unique challenges in diagnosis and treatment.

Key Points

  • Elevated alpha-fetoprotein levels indicate potential pancreatic hepatoid adenocarcinoma, aiding diagnosis.
  • A 46-year-old man exhibited jaundice and a pancreatic head mass, with AFP markedly elevated at diagnosis.
  • Pancreaticoduodenectomy effectively normalized AFP levels post-surgery, emphasizing the need for surgical intervention.
  • Neuroendocrine differentiation complicates both diagnosis and treatment of pancreatic hepatoid adenocarcinoma, calling for careful management.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68af453aad7bf08b1ead2972https://doi.org/10.3389/fonc.2025.1652925
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Alpha-Fetoprotein-producing Neuroendocrine Carcinoma of the Pancreas with Multiple Liver Metastasis: A Case Report2026
  2. 2A 68-Year-Old Man With Neutrophil-Rich Hepatoid Adenocarcinoma of the Gallbladder2026
  3. 3A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series2026
  4. 4An Interesting Case of Alpha-Fetoprotein (AFP)-Producing Pancreaticoduodenal Tumor2024 · 1 citations
  5. 5Case Report: AFP-producing gastric hepatoid adenocarcinoma with multiple liver metastases – integrating quantitative imaging and diagnostic decision analysis2026