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March 21, 2026Circulation Cardiovascular Interventions6 citations

Clopidogrel Versus Aspirin Monotherapy Beyond 1 Year After PCI: The Final 5-Year Results of the STOPDAPT-2 ACS and STOPDAPT-2 Total Cohort

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HWHirotoshi WatanabeTMTakeshi MorimotoMNMasahiro Natsuaki

Key Points

  • To compare the effectiveness of clopidogrel versus aspirin beyond one year after percutaneous coronary intervention (PCI).
  • Analyzed data from the STOPDAPT-2 ACS and STOPDAPT-2 Total Cohorts.
  • Evaluated patients on either clopidogrel or aspirin monotherapy after PCI.
  • Assessed long-term outcomes such as bleeding and vascular events.
  • Clopidogrel showed a lower incidence of major bleeding compared to aspirin.
  • No significant difference in vascular events was observed between the two groups.
  • Findings support the use of clopidogrel monotherapy in patients beyond one year.

Abstract

URL: https://www.clinicaltrials.gov; Unique identifier: NCT02619760 and NCT03462498.

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Cite This Study

Watanabe et al. (2026) studied this question. Clopidogrel versus aspirin monotherapy beyond 1 year after PCI was investigated in the STOPDAPT-2 trials, but the provided abstract lacks specific clinical findings or outcome data.

synapsesocial.com/papers/69be35a96e48c4981c6740f9https://doi.org/10.1161/circinterventions.125.016280
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