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March 1, 2026HLA

Genomic Extension of HLA‐C*03:31 , by Next‐Generation Sequencing

Jarret Merschman Derek Benidt Justin D. Kreuter Laurie L. Wakefield Manish J. Gandhi

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Key Points

To investigate the genomic characteristics of the HLA-C*03:31 allele through advanced sequencing techniques.
Utilized next-generation sequencing for comprehensive genomic analysis.
Focused on exon 2 of the HLA-C gene.
Identified nucleotide substitutions at specific genomic positions.
Characterized a specific nucleotide substitution at genomic position 400.
Established the genomic structure of the HLA-C*03:31 allele.

Implication

Exploratory analysis identifies a nucleotide substitution at genomic position 400 in HLA-C*03:31, suggesting its significance.

Abstract

The HLA-C*03:31 allele is characterised by a nucleotide substitution at genomic DNA position 400 in exon 2.

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Cite This Study

Merschman et al. (2026) studied this question.

synapsesocial.com/papers/69be35a96e48c4981c674122 https://doi.org/10.1111/tan.70655

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