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This research aims to evaluate how storing canine platelet concentrates at 4°C for 14 days affects their function and viability.

Assessment of Platelet Storage Lesions, Viability, and Function in Canine Platelet Concentrate Units Stored at 4°C for 14 Days

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Prospective study assesses platelet viability and function in canine platelet concentrates, highlighting implications for storage and usage.

This research aims to evaluate how storing canine platelet concentrates at 4°C for 14 days affects their function and viability.
Conducted a prospective, in vitro experimental study with canine platelet concentrate units.
Stored six units of platelet concentrate at 4°C for 14 days without agitation.
Tested parameters included platelet counts, lactate levels, aggregometry, and bacterial cultures on various days.
Platelet counts remained stable above 500,000/µL throughout the storage period.
Lactate concentration significantly increased from 2.1 mmol/L to 9.6 mmol/L by Day 14 (p < 0.0001).
Platelet function varied with time; ADP-induced aggregation was minimal, while thrombin showed a better response until Day 12.

Farrell et al. (2026) studied this question.

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Prospective study assesses platelet viability and function in canine platelet concentrates, highlighting implications for storage and usage.