What question did this study set out to answer?

This research aims to understand how various factors affect the movement of elastic vesicles in stenosed arteries, which is important for cardiovascular health.

March 21, 2026Physics of Fluids

Migration dynamics and hydrodynamic resistance of elastic vesicles in deformable stenosed arteries: A fluid–structure interaction study

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Authors

SPSouvik PabiIndian Institute of Technology Patna ARAbhishek RajIndian Institute of Technology Patna MKMohd. Kaleem KhanIndian Institute of Technology Patna

Discussion

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Implication

Fluid-structure interaction study uncovers vesicle transport dynamics in stenosed arteries, suggesting implications for cardiovascular health.

Key Points

This research aims to understand how various factors affect the movement of elastic vesicles in stenosed arteries, which is important for cardiovascular health.
Developed a coupled arbitrary Lagrangian–Eulerian and phase-field model.
Simulated elastic vesicle transport under varied stenosis conditions.
Examined effects of stenosis geometry, severity, and arterial wall stiffness on vesicle dynamics.
Elliptical stenosis significantly increases vesicle velocity, wall shear stress, and hydraulic resistance.
Sinusoidal stenosis maintains thicker lubrication layers, minimizing hemolysis risk.
Increasing stenosis severity causes nonlinear amplification of vesicle dynamics including velocity and pressure.
Arterial stiffening notably enhances vesicle transport and hydraulic resistance.
Vesicle size and membrane elasticity greatly influence deformation and lubrication dynamics.

Cite This Study

Pabi et al. (2026) studied this question.

synapsesocial.com/papers/69be36d46e48c4981c675fb7 https://doi.org/10.1063/5.0314137

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March 21, 2026Physics of Fluids

Migration dynamics and hydrodynamic resistance of elastic vesicles in deformable stenosed arteries: A fluid–structure interaction study

View Full Paper

Ask AI

Bookmark

Authors

SPSouvik PabiIndian Institute of Technology Patna ARAbhishek RajIndian Institute of Technology Patna MKMohd. Kaleem KhanIndian Institute of Technology Patna

Discussion

Member takes

Implication

Fluid-structure interaction study uncovers vesicle transport dynamics in stenosed arteries, suggesting implications for cardiovascular health.

Key Points

This research aims to understand how various factors affect the movement of elastic vesicles in stenosed arteries, which is important for cardiovascular health.
Developed a coupled arbitrary Lagrangian–Eulerian and phase-field model.
Simulated elastic vesicle transport under varied stenosis conditions.
Examined effects of stenosis geometry, severity, and arterial wall stiffness on vesicle dynamics.
Elliptical stenosis significantly increases vesicle velocity, wall shear stress, and hydraulic resistance.
Sinusoidal stenosis maintains thicker lubrication layers, minimizing hemolysis risk.
Increasing stenosis severity causes nonlinear amplification of vesicle dynamics including velocity and pressure.
Arterial stiffening notably enhances vesicle transport and hydraulic resistance.
Vesicle size and membrane elasticity greatly influence deformation and lubrication dynamics.

Cite This Study

Pabi et al. (2026) studied this question.

synapsesocial.com/papers/69be36d46e48c4981c675fb7 https://doi.org/10.1063/5.0314137

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