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March 21, 2026JACC Advances3 citationsOpen Access

Artificial Intelligence–Driven Electrocardiogram Screening for Asymptomatic Left Ventricular Systolic Dysfunction in the General Population

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TRTae-Min RheeSKSora KangMLMin Sung Lee

Key Result

Artificial intelligence-driven ECG screening using the AiTiALVSD model demonstrated high diagnostic accuracy as a rule-out tool for asymptomatic left ventricular systolic dysfunction.

Key Points

  • The study aims to assess the effectiveness of an AI model in screening for asymptomatic left ventricular systolic dysfunction (LVSD).
  • Utilized the AiTiALVSD model for ECG screening
  • Focused on a real-world population with low LVSD prevalence
  • Assessed the model's diagnostic accuracy as a screening tool
  • AiTiALVSD model showed high diagnostic accuracy for detecting LVSD
  • Supports potential use as a rule-out tool for heart failure prevention
  • Prospective validation needed for further confirmation

Structured PICO

Does AI-driven ECG screening accurately detect asymptomatic left ventricular systolic dysfunction in the general population?

P
Population
General population with an extremely low prevalence of asymptomatic left ventricular systolic dysfunction (LVSD)
I
Intervention
Artificial Intelligence-Driven Electrocardiogram Screening (AiTiALVSD model)
O
Outcome
Diagnostic accuracy for asymptomatic LVSDsurrogate

An AI-driven ECG model shows high diagnostic accuracy for detecting asymptomatic LVSD in a general screening population, suggesting utility as a rule-out tool for heart failure prevention.

Limitations

  • Lacks prospective validation

Abstract

In a real-world screening population with an extremely low prevalence of LVSD, the AiTiALVSD model demonstrated high diagnostic accuracy, supporting its potential role as a rule-out screening tool for HF prevention. Prospective validation is warranted.

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Cite This Study

Rhee et al. (2026) studied this question. Artificial intelligence-driven ECG screening using the AiTiALVSD model demonstrated high diagnostic accuracy as a rule-out tool for asymptomatic left ventricular systolic dysfunction.

synapsesocial.com/papers/69be372b6e48c4981c676a12https://doi.org/10.1016/j.jacadv.2026.102660
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