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Case report reveals apocrine ductal carcinoma in situ developing from pleomorphic adenoma in the breast, indicating a rare medical occurrence.
INTRODUCTION: Pleomorphic adenoma (PA) of the breast is an extremely rare benign tumor, and malignant transformation within PA is exceptional. Only a few cases have been reported, and none have described apocrine ductal carcinoma in situ (DCIS) arising in PA. We report a case of apocrine-type DCIS considered to have developed from mammary PA.
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Isono et al. (2026) studied this question.
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