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Compares corneal sensitivity after administering different sodium sulfacetamide concentrations, indicating significant effects with higher doses.
This study compares the effect of 10 and 30% sodium sulfacetamide on corneal sensitivity. The corneal sensitivity was measured on 11 subjects with a Cochet‐Bonnet aesthesiometer without any drug, 10 and 30% sodium sulfacetamide. The results obtained for the mean corneal sensitivities (mean standard error) for the control, 10 and 30% sodium sulfacetamide were 1.07 ± 0.025, 1.09 ± 0.023, and 1.36 ± 0.10 gm/mm 2 , respectively. We found that there was no statistical difference between the control value and 10% sodium sulfacetamide, but the 30% produced a significant decrease in corneal sensitivity when compared to the control and 10% concentration.
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Chang et al. (1984) studied this question.
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