Integrative Breathing Therapy: A Multidimensional Framework for Unified Airway Function and Its Application to Orofacial Myology and Obstructive Sleep Apnea

Background/Objectives: Breathing efficiency and stability depend on the integrated function of biochemical, biomechanical, and psychophysiological processes across the unified upper and lower airway. Clinical interventions often address these domains in isolation, which may limit treatment outcomes. The primary objective of this article is to present Integrative Breathing Therapy (IBT) as a clinically applicable, multidimensional framework for training unified airway function. A secondary objective is to illustrate how this framework can inform clinical reasoning in orofacial myology and behavioural management of obstructive sleep apnea. Method: This article presents a clinical synthesis of physiological theory, neuroplasticity research, and applied breathing therapy to describe the theoretical and clinical foundations underpinning the Integrative Breathing Therapy (IBT) framework. Multidimensional phenotyping is used to organise dominant biochemical, biomechanical, and psychophysiological contributors to breathing inefficiency, with obstructive sleep apnea presented as a clinical example. Results: This synthesis outlines a unified airway model linking multidimensional phenotyping to targeted intervention selection. The IBT framework provides a structured approach for integrating biomechanical coordination, ventilatory control, and psychophysiological regulation within clinical practice. The obstructive sleep apnea exemplar demonstrates how phenotype-informed mapping can support clinical reasoning and guide individualised intervention strategies within OM and related behavioural approaches. Conclusions: Integrative Breathing Therapy offers a clinically grounded, multidimensional model for functional breathing optimisation that aligns unified airway training with principles of neural adaptation and systems-based clinical reasoning. This framework supports phenotype-guided clinical decision-making and provides a coherent structure for addressing breathing inefficiency and airway instability across a range of clinical populations, including those treated with orofacial myology and behavioural OSA therapies.