Correlation of ACR TI-RADS ultrasound classification with cytopathology: a retrospective evaluation of diagnostic accuracy

Şeref Barbaros Arık; Pınar Atabey

doi:10.32322/jhsm.1853967

March 12, 2026Journal of Health Sciences and MedicineOpen Access

Correlation of ACR TI-RADS ultrasound classification with cytopathology: a retrospective evaluation of diagnostic accuracy

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Key Points

Evaluate the diagnostic performance of ACR TI-RADS in predicting thyroid nodule malignancy and assess its correlation with cytopathological outcomes.
Retrospective evaluation of 567 thyroid nodules using ultrasound and Doppler imaging.
TI-RADS scores assigned based on sonographic features according to ACR criteria.
Cytopathological outcomes classified as benign or malignant, serving as the reference standard.
Statistical analysis included sensitivity, specificity, predictive values, accuracy, and AUC calculations.
5.8% of nodules were malignant, with malignancy rates increasing across TI-RADS categories.
Malignancy rates reached 31.6% in TR5 nodules.
Using TI-RADS ≥4, sensitivity was 78.8%, specificity 61.0%, with an accuracy of 62.1% and AUC of 0.75.

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This retrospective evaluation investigates the accuracy of ACR TI-RADS in identifying thyroid nodule malignancy, indicating effective diagnostic strategies.

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Arık et al. (2026) studied this question.

synapsesocial.com/papers/69be38a46e48c4981c6793df https://doi.org/10.32322/jhsm.1853967

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Correlation of ACR TI-RADS ultrasound classification with cytopathology: a retrospective evaluation of diagnostic accuracy

Key Points

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Correlation of ACR TI-RADS ultrasound classification with cytopathology: a retrospective evaluation of diagnostic accuracy

Key Points

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Implication

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