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Histopathological Basis of Peritumoral Enhancement in Muscle-invasive Bladder Cancer | Synapse

March 21, 2026Magnetic Resonance in Medical Sciences0 citationsOpen Access

Histopathological Basis of Peritumoral Enhancement in Muscle-invasive Bladder Cancer

HWHiroyuki WatanabeUniversity of Kochi MTMitsuru TakeuchiTokai Gakuen University AHAtsushi HigakiKawasaki Medical School

Key Points

To investigate the histopathological features contributing to peritumoral enhancement in muscle-invasive bladder cancer.
Conducted histopathological examination of tumor samples
Analyzed stromal characteristics at tumor invasive front
Measured microvessel density in surrounding tissue
Identified significant peritumoral fibrosis around invasive tumors
Increased microvessel density correlated with peritumoral enhancement

Abstract

PTE reflects localized stromal remodeling at the tumor invasive front, characterized predominantly by marked peritumoral fibrosis accompanied by increased microvessel density.

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Watanabe et al. (Thu,) studied this question.

synapsesocial.com/papers/69be38ca6e48c4981c6797cd https://doi.org/https://doi.org/10.2463/mrms.mp.2025-0211

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