Comparative efficacy of intralesional therapies for keloid scars: a network meta-analysis

Key Points

• The aim is to compare the efficacy of various intralesional therapies for keloid scars.
• Conducted a network meta-analysis of available intralesional therapies.
• Evaluated combination therapies including 5-FU, corticosteroids, and YAG laser.
• Considered novel agents like insulin and BTX-A in the evaluation.
• Combination therapies, especially 5-FU + corticosteroids + YAG laser, showed the highest effectiveness.
• Novel agents demonstrated some potential, but further research is necessary.
• Standardized methodologies and longer follow-up are essential for optimal treatment guidelines.